Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684213 | 0.82 | PLA2G4B (0.69) | CA2PLA2G4BLTB4RLTB4R2TBXAS1 | |
| SCHEMBL3026943 | 0.81 | CA12 (0.59) | CA12CA1CA2CA4CA9 | |
| SCHEMBL9517972 | 0.80 | LTB4R (0.63) | PLA2G4BLTB4RLTB4R2TBXAS1ALDH1A1 | |
| SCHEMBL11683055 | 0.80 | PLA2G4B (0.61) | CA2PLA2G4BLTB4RLTB4R2TBXAS1 | |
| SCHEMBL15941568 | 0.78 | TP53 (0.59) | CA12CA1CA2CA4CA9 | |
| SCHEMBL2762936 | 0.78 | PTGS2 (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL11596852 | 0.78 | PLA2G4B (0.56) | PLA2G4BLTB4RLTB4R2TBXAS1ALDH1A1 | |
| SCHEMBL11650853 | 0.77 | TMEM97 (0.49) | CA2PLA2G4BALDH1A1LMNAKDM4E | |
| SCHEMBL1162418 | 0.77 | PLA2G4B (0.59) | CA2PLA2G4BLTB4RLTB4R2TBXAS1 | |
| SCHEMBL10728695 | 0.77 | PLA2G4B (0.59) | PLA2G4BLTB4RLTB4R2TBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951653-B1 | SALICYLIC ACID DERIVATIVES | NICOX SA (FR) | 2010-10-20 | — | — | EP | disclosed |
| US-20100210694-A1 | NEW NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-08-19 | — | — | US | disclosed |
| US-20100210694-A1 | NEW NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-08-19 | — | — | US | disclosed |
| US-20080293781-A1 | Salicylic Acid Derivatives | NICOX S.A. (FR) | 2008-11-27 | — | — | US | disclosed |
| EP-1951653-A1 | SALICYLIC ACID DERIVATIVES | NicOx S.A. (FR) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007060112-A1 | SALICYLIC ACID DERIVATIVES | NICOX S.A. (FR) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293781-A1 | Salicylic Acid Derivatives | PTGS2, PTGS1, PTGES2 | CA12 2846/4885CA1 2747/4885CA2 686/4885 |
| US-20100210694-A1 | NEW NO-DONOR ASPIRIN DERIVATIVES | PTGIS, NOS2, NOS3 | CA12 4800/4885CA1 4743/4885CA2 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.