Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044417 | 0.84 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL5046558 | 0.84 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL5047701 | 0.84 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL6937078 | 0.82 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1897376 | 0.82 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1852799 | 0.78 | LMNA (0.57) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1852798 | 0.78 | FFAR1 (0.52) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL4623168 | 0.76 | FFAR1 (0.46) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL5886652 | 0.74 | FFAR1 (0.63) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL15588318 | 0.74 | FFAR1 (0.42) | FFAR1FFAR4MMP2MMP12ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |