SCHEMBL5046827

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5052725	0.87	RAB9A (0.53)	GAARAB9AMEN1KMT2AALDH1A1
	SCHEMBL15702664	0.86	GAA (0.61)	GAARAB9AMEN1KMT2AALDH1A1
	SCHEMBL15702707	0.86	GAA (0.61)	GAARAB9AMEN1KMT2AALDH1A1
	SCHEMBL5046630	0.86	IL2 (0.70)	GAARAB9AMEN1KMT2AALDH1A1
	SCHEMBL5133373	0.86	GAA (0.56)	GAARAB9AMEN1KMT2AALDH1A1
	SCHEMBL15702663	0.85	GAA (0.55)	GAAMEN1KMT2AALDH1A1IL2
	SCHEMBL5049053	0.84	GAA (0.56)	GAARAB9AMEN1KMT2AALDH1A1
	SCHEMBL12991171	0.84	ALDH1A1 (0.61)	GAARAB9AMEN1KMT2AALDH1A1
	SCHEMBL5049767	0.83	GAA (0.55)	GAARAB9AMEN1KMT2AALDH1A1
	SCHEMBL5049839	0.83	IL2 (0.59)	GAAMEN1KMT2AALDH1A1IL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.