Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134533 | 0.94 | FFAR1 (0.43) | FFAR1PPARGCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5043948 | 0.87 | FFAR1 (0.40) | FFAR1PPARGMARS1CSNK2A2CSNK2B | |
| SCHEMBL5134535 | 0.84 | PRKCB (0.40) | FFAR1PPARGALDH1A1 | |
| SCHEMBL5043913 | 0.82 | FFAR1 (0.41) | FFAR1PPARGKDM4EPOLBALDH1A1 | |
| SCHEMBL5134536 | 0.81 | VSIR (0.43) | FFAR1PPARGKDM4EPOLBALDH1A1 | |
| SCHEMBL5132461 | 0.81 | PRMT5 (0.42) | FFAR1PPARGHPGD | |
| SCHEMBL3046600 | 0.77 | KDR (0.45) | FFAR1PPARGMARS1 | |
| SCHEMBL5133476 | 0.76 | HPGD (0.50) | FFAR1KDM4EPOLBALDH1A1HPGD | |
| SCHEMBL5133013 | 0.71 | CHEK1 (0.47) | FFAR1KDM4EPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL3050162 | 0.69 | AURKA (0.43) | FFAR1PPARGKMT2AVSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |