Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134533 | 0.86 | FFAR1 (0.43) | FFAR1PPARG | |
| SCHEMBL5043948 | 0.86 | FFAR1 (0.40) | FFAR1PPARG | |
| SCHEMBL5046975 | 0.84 | FFAR1 (0.41) | FFAR1PPARGALDH1A1 | |
| SCHEMBL5043913 | 0.82 | FFAR1 (0.41) | FFAR1PPARGALDH1A1 | |
| SCHEMBL5132461 | 0.78 | PRMT5 (0.42) | FFAR1PPARGHTT | |
| SCHEMBL3040020 | 0.77 | AURKA (0.42) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL5134536 | 0.76 | VSIR (0.43) | FFAR1PPARGALDH1A1 | |
| SCHEMBL5079421 | 0.73 | KDR (0.58) | ALDH1A1 | |
| SCHEMBL5133476 | 0.71 | HPGD (0.50) | FFAR1HTTALDH1A1 | |
| SCHEMBL14286557 | 0.69 | L3MBTL1 (0.52) | L3MBTL1HTTRAD52PAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |