⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753695 | 0.75 | — | — | |
| SCHEMBL19042436 | 0.75 | CA12 (0.38) | — | |
| SCHEMBL576260 | 0.73 | MEN1 (0.48) | — | |
| SCHEMBL223757 | 0.73 | FBP1 (0.52) | — | |
| SCHEMBL19042227 | 0.73 | — | — | |
| SCHEMBL9338177 | 0.71 | — | — | |
| SCHEMBL15199481 | 0.71 | — | — | |
| SCHEMBL13499 | 0.71 | — | — | |
| SCHEMBL5043896 | 0.69 | KIF11 (0.46) | — | |
| SCHEMBL21886055 | 0.69 | SLC6A4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504329-A | Axial chiral sulfilimine compound and preparation method and application thereof | 安徽农业大学 | 2025-02-25 | — | — | CN | disclosed |
| US-20240027902-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-01-25 | — | — | US | disclosed |
| US-11774853-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-10-03 | — | — | US | disclosed |
| EP-3514157-B1 | METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORP (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2023285787-A1 | SULFUR COMPOUNDS AND PROCESSES AND INTERMEDIATES USEFUL IN THE PREPARATION THEREOF | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023285788-A1 | SULFUR COMPOUNDS AND PROCESSES AND INTERMEDIATES USEFUL IN THE PREPARATION THEREOF | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-01-19 | — | — | WO | disclosed |
| US-11415887-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-08-16 | — | — | US | disclosed |
| US-20210302838-A1 | RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-09-30 | — | — | US | disclosed |
| US-10954230-B2 | Method of preparing glucosylceramide synthase inhibitors | GENZYME CORPORATION (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200272048-A1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-08-27 | — | — | US | disclosed |
| US-20160039806-A1 | METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION | 2016-02-11 | — | — | US | disclosed |
| EP-2970251-A1 | METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | Genzyme Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151291-A1 | METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2014-09-25 | — | — | WO | disclosed |
| EP-1583762-B1 | PYRROLYL-THIAZOLES AND THEIR USE AS CB 1 RECEPTOR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007044693-A2 | MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS | THE UNIVERSITY OF ALABAMA (US) | 2007-04-19 | — | — | WO | disclosed |
| US-7135488-B2 | Pyrrolyl-thiazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-11-14 | — | — | US | disclosed |
| EP-1583762-A1 | PYRROLYL-THIAZOLES AND THEIR USE AS CB 1 RECEPTOR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-12 | — | — | EP | disclosed |
| US-20040147572-A1 | Novel pyrrolyl-thiazole derivatives | HOFFMAN-LA ROCHE INC. | 2004-07-29 | — | — | US | disclosed |
| WO-2004060888-A1 | NOVEL CB 1 RECEPTOR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-22 | — | — | WO | disclosed |
| EP-0538097-A1 | Naphthalene-1-acetic-acid derivatives, their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-04-21 | — | — | EP | disclosed |