SCHEMBL576260

SCHEMBL576260

Fc1ccc(Sc2ccc(F)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
MAPT P10636 2/20 0.48
NR1H2 P55055 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
ACHE P22303 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 2/20 0.40
DDAH1 O94760 1/20 0.40
NOS1 P29475 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4115867 0.91 MEN1 (0.44) MEN1KMT2AMAPTNR1H2CYP3A4
SCHEMBL11980111 0.88 MAOA (0.50) MEN1KMT2AMAPTCYP3A4MAPK1
SCHEMBL775694 0.88 MAOA (0.50) MEN1KMT2AMAPTCYP3A4MAPK1
SCHEMBL7937917 0.86 MAOA (0.52) MEN1KMT2AMAPTNR1H2CYP3A4
SCHEMBL6068324 0.86 MAPK1 (0.74) MEN1KMT2AMAPTCYP3A4TSHR
SCHEMBL7937262 0.86 MEN1 (0.55) MEN1KMT2AMAPTCYP3A4TSHR
SCHEMBL9440388 0.86 MEN1 (0.44) MEN1KMT2AMAPTNR1H2CYP3A4
SCHEMBL7938033 0.86 ACHE (0.68) MEN1KMT2AMAPTTSHRCYP1A2
SCHEMBL11491768 0.84 DDAH1 (0.70) MEN1KMT2AMAPTDDAH1NOS1
SCHEMBL5685447 0.84 MEN1 (0.40) MEN1KMT2AMAPTNR1H2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076387-A1 MULTIBLOCK COPOLYMERS FOR MOISTURE SWING DIRECT AIR CAPTURE ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-04-10 WO claimed
CN-116041153-B Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2024-05-24 CN claimed
CN-116041153-A Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2023-05-02 CN claimed
EP-1752463-B1 NOVEL FLUORINATED ALKYLFLUOROPHOSPHORIC ACID SALT OF ONIUM AND TRANSITION METAL COMPLEX SAN APRO LTD (JP) 2013-07-17 EP claimed
WO-2025076387-A1 MULTIBLOCK COPOLYMERS FOR MOISTURE SWING DIRECT AIR CAPTURE ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-04-10 WO disclosed
CN-116283684-B Green preparation method of diphenyl sulfide and derivative thereof 常州大学 2025-04-08 CN disclosed
CN-119504523-A Preparation method of fluorine-containing phenyl sulfoxide compound 苏州源起材料科技有限公司 2025-02-25 CN disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20240297344-A1 NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-05 US disclosed
CN-116041153-B Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2024-05-24 CN disclosed
CN-111406233-B Photosensitive resin composition, dry film resist and cured product thereof 日本化药株式会社 2023-12-26 CN disclosed
US-11809078-B2 Photosensitive resin composition, dry film resist, and cured objects obtained therefrom NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2023-11-07 US disclosed
US-5276037-A Antiinflammatory agents, antiallergens IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-04 US disclosed
US-5272173-A 5-lipoxygenase inhibitors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-21 US disclosed
US-5225438-A Lipoxygenase inhibitors for antiinflammatory agents or antiallergens IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-07-06 US disclosed
EP-0488602-A1 Aryl derivatives ZENECA LIMITED (GB) 1992-06-03 EP disclosed
US-4906712-A Process for the preparation of polyarylene sulphides BAYER AKTIENGESELLSCHAFT (DE) 1990-03-06 US disclosed
US-4533497-A N-ethylidene azetidinones ELI LILLY AND COMPANY (US) 1985-08-06 US disclosed
US-4339611-A BUTANOL, BUTANAL, COBALT, IODINE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-07-13 US disclosed
US-3988467-A Aminoacyl compounds CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed