Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | RARG | P13631 | 3/20 | 0.45 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047204 | 1.00 | LMNA (0.52) | LMNAMAPTNPC1HTTRAB9A | |
| SCHEMBL9187421 | 0.85 | CYP26A1 (0.60) | LMNAMAPTNPC1HTTRAB9A | |
| SCHEMBL9187417 | 0.85 | CYP26A1 (0.60) | LMNAMAPTNPC1HTTRAB9A | |
| SCHEMBL5047251 | 0.79 | MAOB (0.48) | LMNAMAPTNPC1HTTRAB9A | |
| SCHEMBL5047257 | 0.79 | MAOB (0.48) | LMNAMAPTNPC1HTTRAB9A | |
| SCHEMBL5047115 | 0.76 | RARB (0.53) | CYP26A1RARBRARGRARACYP3A4 | |
| SCHEMBL1615329 | 0.74 | RARB (0.72) | LMNAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL1615774 | 0.74 | RARB (0.72) | LMNAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL1615332 | 0.74 | RARB (0.72) | LMNAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL1406271 | 0.74 | XDH (0.59) | LMNAMAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326803-B2 | Ligand inhibitors of the RAR receptors, process for preparing same and therapeutic/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-02-05 | — | — | US | disclosed |
| US-20050148670-A1 | Novel ligand inhibitors of the RAR receptors, process for preparing same and therapeutic/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148670-A1 | Novel ligand inhibitors of the RAR receptors, process for preparing same and therapeutic/cosmetic applications thereof | RARA, RARB, RARG | LMNA 3890/4885MAPT 4731/4885NPC1 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.