Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044438 | 0.91 | ACACB (0.43) | TAAR1PPARGPPARAMIFPSMB5 | |
| SCHEMBL5048897 | 0.76 | ACACB (0.35) | MAOB | |
| SCHEMBL1696674 | 0.76 | TAAR1 (0.61) | TAAR1DAOMIFMAOB | |
| SCHEMBL5046020 | 0.76 | PPARG (0.53) | PPARGPPARAEPHX2 | |
| Ammonia Solution, Strong SCHEMBL6193177 | 0.75 | TAAR1 (0.59) | TAAR1DAOMIFMAOB | |
| SCHEMBL5045018 | 0.74 | TP53 (0.45) | — | |
| SCHEMBL8990753 | 0.73 | MAOB (0.61) | TAAR1DAOMIFMAOB | |
| SCHEMBL9809579 | 0.71 | MAOB (0.63) | TAAR1DAOMIFMAOB | |
| SCHEMBL934227 | 0.69 | TAAR1 (0.73) | TAAR1DAOMIFMAOB | |
| SCHEMBL6660765 | 0.69 | MEN1 (0.42) | TAAR1PPARGPPARAPDE2APSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |