Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047575 | 0.83 | MEN1 (0.50) | MEN1KMT2ARXFP1MLYCDNAMPT | |
| SCHEMBL5048870 | 0.80 | MLYCD (0.52) | MEN1KMT2AMLYCDNAMPTHDAC6 | |
| SCHEMBL1854683 | 0.80 | MEN1 (0.46) | MEN1KMT2ARXFP1MLYCDNAMPT | |
| SCHEMBL5048692 | 0.74 | MEN1 (0.43) | MEN1KMT2ARXFP1HDAC4NPC1 | |
| SCHEMBL6023305 | 0.74 | MEN1 (0.43) | MEN1KMT2ARXFP1HDAC4NPC1 | |
| SCHEMBL5969299 | 0.73 | ESRRG (0.73) | MLYCDNAMPTNPC1RAB9AESRRG | |
| SCHEMBL3062674 | 0.73 | MLYCD (0.76) | MEN1KMT2AMLYCDNAMPTHDAC4 | |
| SCHEMBL5044168 | 0.72 | ALDH1A1 (0.47) | MLYCDNAMPTHDAC2PPARG | |
| SCHEMBL5045562 | 0.72 | ALDH1A1 (0.47) | MLYCDNAMPTHDAC2PPARG | |
| SCHEMBL5045572 | 0.72 | ALDH1A1 (0.49) | MEN1KMT2AMLYCDNAMPTHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |