Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854634 | 0.88 | STAT3 (0.44) | NAAASTAT3HDAC3SIGMAR1TMEM97 | |
| SCHEMBL5044268 | 0.88 | NAAA (0.60) | NAAAHDAC3SIGMAR1TMEM97HPGD | |
| SCHEMBL5047455 | 0.88 | MEN1 (0.48) | HDAC3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5045478 | 0.85 | NAAA (0.54) | NAAASTAT3SIGMAR1TMEM97MEN1 | |
| SCHEMBL5045568 | 0.85 | FOLH1 (0.46) | NAAASIGMAR1TMEM97HPGDMEN1 | |
| SCHEMBL27619621 | 0.85 | NAAA (0.48) | NAAAHDAC3HPGDMEN1NPC1 | |
| SCHEMBL5044933 | 0.83 | LMNA (0.46) | STAT3HPGDSMN1; SMN2MAPK14 | |
| SCHEMBL5048866 | 0.82 | NPC1 (0.48) | HDAC3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5040041 | 0.82 | NAAA (0.48) | NAAAHDAC3SIGMAR1TMEM97HPGD | |
| SCHEMBL5044795 | 0.80 | MEN1 (0.45) | HDAC3MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |