Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044268 | 0.91 | NAAA (0.60) | NAAASIGMAR1TMEM97MEN1NPC1 | |
| SCHEMBL5039808 | 0.90 | GAA (0.56) | NAAASIGMAR1GAAMAPTSMN1; SMN2 | |
| SCHEMBL1854062 | 0.89 | NAAA (0.51) | NAAASIGMAR1TMEM97GAAMAPT | |
| SCHEMBL5040331 | 0.86 | SMN1; SMN2 (0.54) | NAAASIGMAR1TMEM97SMN1; SMN2 | |
| SCHEMBL1856151 | 0.86 | NAAA (0.47) | NAAASIGMAR1TMEM97GAAMAPT | |
| SCHEMBL5047697 | 0.85 | NAAA (0.46) | NAAASIGMAR1TMEM97SMN1; SMN2MEN1 | |
| SCHEMBL27601103 | 0.85 | NAAA (0.56) | NAAAGAAMAPTSMN1; SMN2 | |
| SCHEMBL5041082 | 0.83 | NAAA (0.60) | NAAASIGMAR1TMEM97SMN1; SMN2KMT2A | |
| SCHEMBL5039921 | 0.83 | SMN1; SMN2 (0.56) | NAAASIGMAR1TMEM97SMN1; SMN2NPC1 | |
| SCHEMBL5039801 | 0.82 | SIGMAR1 (0.53) | NAAASIGMAR1TMEM97GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |