Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 10/20 | 0.51 |
| ▸ | CA1 | P00915 | 9/20 | 0.51 |
| ▸ | CA9 | Q16790 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753653 | 1.00 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10CA12 | |
| SCHEMBL12128029 | 1.00 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10CA12 | |
| SCHEMBL543668 | 1.00 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10CA12 | |
| SCHEMBL543667 | 1.00 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10CA12 | |
| SCHEMBL16383664 | 1.00 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10CA12 | |
| SCHEMBL29709529 | 0.94 | CA2 (0.53) | CA2CYP2D6THRBHSD17B10CA12 | |
| SCHEMBL29709523 | 0.94 | CA2 (0.53) | CA2CYP2D6THRBHSD17B10CA12 | |
| SCHEMBL29601003 | 0.90 | CYP2D6 (0.55) | CA2CYP2D6THRBHSD17B10CA12 | |
| SCHEMBL13640512 | 0.86 | CA2 (0.43) | CA2CYP2D6THRBHSD17B10CA12 | |
| SCHEMBL6322620 | 0.84 | LMNA (0.57) | CA2CYP2D6THRBHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808020-A | Optical reaction cell and light source for 18F! fluoride radiotracer synthesis | ASSOCIATED UNIVERSITIES, INC. (US) | 1998-09-15 | — | — | US | claimed |
| US-8206593-B2 | Adapted for on-chip solvent exchange; synthesis of radiopharmaceuticals such as FDG (fludeoxyglucose F18) for example | FLUIDIGM CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| US-20080281090-A1 | Microfluidic Chemical Reaction Circuits | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-11-13 | — | — | US | disclosed |
| US-5808020-A | Optical reaction cell and light source for 18F! fluoride radiotracer synthesis | ASSOCIATED UNIVERSITIES, INC. (US) | 1998-09-15 | — | — | US | disclosed |