Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21412297 | 0.80 | AOC3 (0.47) | AOC3METNPC1RAB9ACHRM2 | |
| Ammonia Solution, Strong SCHEMBL28862485 | 0.80 | AOC3 (0.43) | AOC3NPC1RAB9ACHRM2CHRM3 | |
| SCHEMBL5053616 | 0.80 | AOC3 (0.47) | AOC3METNPC1RAB9ACHRM2 | |
| SCHEMBL11730368 | 0.80 | KEAP1 (0.55) | AOC3NPC1RAB9ACHRM2CHRM3 | |
| SCHEMBL5048013 | 0.80 | AOC3 (0.43) | AOC3NPC1RAB9ACHRM2CHRM3 | |
| SCHEMBL27255898 | 0.79 | EP300 (0.44) | AOC3ALDH1A1LMNAKDM1AF2RL3 | |
| SCHEMBL23328880 | 0.77 | AOC3 (0.42) | AOC3NPC1RAB9ACHRM2CHRM3 | |
| SCHEMBL5047974 | 0.77 | AOC3 (0.51) | AOC3METNPC1RAB9AALDH1A1 | |
| SCHEMBL6967960 | 0.76 | KCNH2 (0.50) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL22918654 | 0.76 | AOC3 (0.50) | AOC3CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |