Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328880 | 0.81 | AOC3 (0.42) | AOC3NOTUMTP53USP2NPC1 | |
| SCHEMBL21412297 | 0.80 | AOC3 (0.47) | AOC3TP53USP2NPC1RAB9A | |
| SCHEMBL5047902 | 0.80 | AOC3 (0.47) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5053616 | 0.80 | AOC3 (0.47) | AOC3METAP2TP53MAPK1NPC1 | |
| SCHEMBL11730368 | 0.80 | KEAP1 (0.55) | AOC3METAP2TP53NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL28862485 | 0.80 | AOC3 (0.43) | AOC3NOTUMMETAP2TP53NPC1 | |
| SCHEMBL5049537 | 0.79 | AHR (0.45) | AOC3NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5049416 | 0.77 | CHRM2 (0.43) | NOTUMMETAP2MAPK1NPC1RAB9A | |
| SCHEMBL5047974 | 0.77 | AOC3 (0.51) | AOC3MAPK1NPC1RAB9AMAPT | |
| SCHEMBL22918654 | 0.76 | AOC3 (0.50) | AOC3CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |