Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | KMO | O15229 | 5/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048013 | 0.79 | AOC3 (0.43) | KCNH2MAPTNPC1NFKB1RAB9A | |
| SCHEMBL27570607 | 0.79 | AHR (0.45) | AHRKCNH2KMOF2RL3CYP1A2 | |
| SCHEMBL14648841 | 0.74 | KEAP1 (0.53) | AHRKCNH2KMOF2RL3CYP1A2 | |
| SCHEMBL29598873 | 0.74 | KEAP1 (0.53) | AHRKCNH2KMOF2RL3CYP1A2 | |
| SCHEMBL31168042 | 0.74 | CHRM2 (0.38) | BRD4BRD3AOC3 | |
| SCHEMBL17809711 | 0.72 | KCNH2 (0.45) | KCNH2KMOHSD11B1BRD4BRD3 | |
| SCHEMBL5053616 | 0.72 | AOC3 (0.47) | KCNH2MAPTBRD4BRD3NPC1 | |
| Ammonia Solution, Strong SCHEMBL28862485 | 0.72 | AOC3 (0.43) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL3223296 | 0.71 | KMT2A (0.49) | AHRKMOF2RL3MAPTNPC1 | |
| SCHEMBL25732008 | 0.71 | IDO1 (0.49) | KMONPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |