Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL5048085

O=S(=O)(O)C(F)(F)F.S=c1c2ccccc2oc2c(S)cccc12

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.38
CDC14B O60729 8/20 0.35
CDC14A Q9UNH5 8/20 0.35
EGFR P00533 1/20 0.33
KDM5A P29375 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2E1 P05181 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2A6 P11509 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP4B1 P13584 1/20 0.32
CYP2B6 P20813 1/20 0.32
CYP3A5 P20815 1/20 0.32
CYP2A7 P20853 1/20 0.32
CYP3A7 P24462 1/20 0.32
CYP2F1 P24903 1/20 0.32
CYP2C18 P33260 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5046429 0.88 CDC14B (0.32) MAOACDC14BCDC14AKDM5A
Trifluoromethanesulfonic Acid SCHEMBL6879347 0.85 MAOA (0.56) MAOAEGFRKDM5ACYP3A4PTGS2
Trifluoromethanesulfonic Acid SCHEMBL5046279 0.79 MAOA (0.35) MAOACDC14BCDC14ACYP1A2CYP3A4
Dibenzofuran SCHEMBL21611805 0.75 MAOA (0.48) MAOACDC14BCDC14ACYP1A2CYP3A4
Trifluoromethanesulfonic Acid SCHEMBL6881212 0.72 CYP2A6 (0.42) MAOACDC14BCDC14ACYP3A4CYP2A6
SCHEMBL9851906 0.72 MAOA (0.64) MAOAEGFRKDM5ACYP3A4CYP2D6
SCHEMBL9349902 0.71 ALOX5 (0.46) MAOAKDM5ACYP3A4CYP2C19ALOX5
Trifluoromethanesulfonic Acid SCHEMBL6249524 0.70 CYP1A2 (0.41) CYP1A2KDM4EPTPN1
Trifluoromethanesulfonic Acid SCHEMBL3519717 0.70 MAOA (0.33) MAOACDC14BCDC14AALDH1A1
SCHEMBL3519718 0.69 PTGES2 (0.32) MAOACDC14BCDC14AKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-B1 HETEROCYCLE-BEARING ONIUM SALTS WAKO PURE CHEM IND LTD (JP) 2008-12-31 EP disclosed
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed