SCHEMBL9349902

SCHEMBL9349902

Sc1cccc2c1oc1ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.46
AHR P35869 3/20 0.44
MAOA P21397 3/20 0.43
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 3/20 0.41
HPGD P15428 3/20 0.41
GLA P06280 1/20 0.41
CYP3A4 P08684 1/20 0.41
PGAM1 P18669 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
CYP2C19 P33261 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
LMNA P02545 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1635471 0.79 AHR (0.52) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL13564032 0.79 AHR (0.52) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL20172232 0.77 IDO1 (0.38) CYP3A4CYP2C19LMNA
SCHEMBL20308237 0.77 PSMD14 (0.47) KDM4EALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL10945864 0.77 ALOX5 (0.68) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL329525 0.76 ALDH1A1 (0.48) AHRMAOAKDM4EALDH1A1SMN1; SMN2
SCHEMBL30241451 0.76 ALDH1A1 (0.48) AHRMAOAKDM4EALDH1A1SMN1; SMN2
SCHEMBL5028273 0.76 ALOX5 (0.66) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL431458 0.76 ALOX5 (0.66) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL27455696 0.76 ALOX5 (0.47) ALOX5AHRMAOAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11858952-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-01-02 US disclosed
US-11858952-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-01-02 US disclosed
US-11858952-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-01-02 US disclosed
CN-112513051-B Compound and color conversion film comprising the same 株式会社LG化学 2023-12-26 CN disclosed
US-11753421-B2 Silylated derivatives of aromatic heterocycles CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-09-12 US disclosed
EP-4225006-A2 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2023-08-09 EP disclosed
US-20220402942-A1 COMPOUND AND OPTICAL FILM COMPRISING SAME LG CHEM, LTD. (KR) 2022-12-22 US disclosed
CN-110551015-B Compound and organic light-emitting element using same 株式会社LG化学 2022-06-21 CN disclosed
US-20210347790-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME LG CHEM, LTD. (KR) 2021-11-11 US disclosed
US-20210347790-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME LG CHEM, LTD. (KR) 2021-11-11 US disclosed
CN-112513051-A Compound and color conversion film comprising same 株式会社LG化学 2021-03-16 CN disclosed
EP-3693372-A1 BENZOFURO[3',2':4,5]IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN ORGANIC LIGHT-EMITTING DEVICES (OLEDS) Samsung Display Co., Ltd. (KR) 2020-08-12 EP disclosed
EP-3301097-A2 [1]BENZOTHIENO[3',2':4,5]IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN ORGANIC LIGHT-EMITTING DEVICES (OLEDS) Samsung Display Co., Ltd. (KR) 2018-04-04 EP disclosed
EP-3229290-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-10-11 EP disclosed
EP-0340010-B1 Heterocyclic nitromethane derivatives ICI PLC (GB) 1994-08-24 EP disclosed
US-5102905-A For treating side effects of diabetes and galactosemia IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-07 US disclosed
EP-0340010-A2 Heterocyclic nitromethane derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11753421-B2 Silylated derivatives of aromatic heterocycles KCNH1, KCNH3, HNRNPH3 ALOX5 3248/4885AHR 40/4885MAOA 1741/4885
US-20220402942-A1 COMPOUND AND OPTICAL FILM COMPRISING SAME CDH1, OR10J3, CRY1 ALOX5 1233/4885AHR 2975/4885MAOA 263/4885
US-20210347790-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME BLVRB, CDYL, CRY1 ALOX5 1651/4885AHR 3648/4885MAOA 39/4885
US-11858952-B2 Compound and color conversion film comprising same BLVRB, CDYL, CRY1 ALOX5 1651/4885AHR 3648/4885MAOA 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.