Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265333 | 0.87 | PDE4A (0.46) | PNPGDAPDE4APDE4BPDE4C | |
| SCHEMBL6267419 | 0.84 | PNP (0.40) | PNPKDM4E | |
| SCHEMBL6268075 | 0.84 | ADORA2A (0.34) | PNPGDAPDE4APDE4BPDE4C | |
| SCHEMBL6265529 | 0.83 | PDE4A (0.34) | PNPALDH1A1GDAPDE4APDE4B | |
| SCHEMBL9960806 | 0.83 | PNP (0.38) | PNPPDE4APDE4BPDE4CPDE4D | |
| Propionic Acid SCHEMBL11016684 | 0.82 | PDE4A (0.43) | PNPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5104179 | 0.81 | HPRT1 (0.35) | — | |
| SCHEMBL7758685 | 0.81 | PDE4A (0.33) | PNPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6266771 | 0.81 | CDK1 (0.36) | PNPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6271696 | 0.81 | PNP (0.39) | PNPKDM4EALDH1A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | claimed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | claimed |
| EP-1873156-A1 | Process for the preparation of 6-[[(alkoxy)carbonyl]amino]-9H-Purine-9-acetic acid and 4-[(alkoxycarbonyl)amino]-2-oxo-1(2H)-Pyrimidineacetic acid derivatives as synthons for the synthesis of peptide nucleic acids | PerSeptive Biosystems, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-0736027-B1 | GUANINE SYNTHONS FOR PEPTIDE NUCLEIC ACID SYNTHESIS AND METHOD FOR PRODUCTION | PERSEPTIVE BIOSYSTEMS INC (US) | 2002-05-29 | — | — | EP | disclosed |
| US-6172226-B1 | Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions | PERSEPTIVE BIOSYSTEMS, INC. | 2001-01-09 | — | — | US | disclosed |
| US-6133444-A | PURINE PEPTIDE NUCLEIC ACIDS SYNTHONS | PERSEPTIVE BIOSYSTEMS, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0840736-A1 | IMPROVED SYNTHONS FOR THE SYNTHESIS AND DEPROTECTION OF PEPTIDE NUCLEIC ACIDS UNDER MILD CONDITIONS | PerSeptive Biosystems, Inc. (US) | 1998-05-13 | — | — | EP | disclosed |
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996040685-A1 | IMPROVED SYNTHONS FOR THE SYNTHESIS AND DEPROTECTION OF PEPTIDE NUCLEIC ACIDS UNDER MILD CONDITIONS | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0736027-A1 | GUANINE SYNTHONS FOR PEPTIDE NUCLEIC ACID SYNTHESIS AND METHOD FOR PRODUCTION | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |
| WO-1995017403-A1 | GUANINE SYNTHONS FOR PEPTIDE NUCLEIC ACID SYNTHESIS AND METHOD FOR PRODUCTION | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1995-06-29 | — | — | WO | disclosed |