SCHEMBL9960806

SCHEMBL9960806

Nc1nc2[nH]cnc2c(=O)n1Cn1c(N)nc2[nH]cnc2c1=O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PNP P00491 2/20 0.38
ADORA2A P29274 11/20 0.34
ADORA2B P29275 9/20 0.34
PDE4A P27815 8/20 0.33
PDE4B Q07343 8/20 0.33
PDE4C Q08493 8/20 0.33
PDE4D Q08499 8/20 0.33
ABL1 P00519 1/20 0.33
RIN1 Q13671 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
MAPT P10636 1/20 0.33
PARP1 P09874 1/20 0.33
ADORA3 P0DMS8 2/20 0.32
KDM4A O75164 1/20 0.31
KDM4B O94953 1/20 0.31
KDM5C P41229 1/20 0.31
KDM5B Q9UGL1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL874734 0.87 ADORA2A (0.45) PNPADORA2AADORA2BPDE4APDE4B
SCHEMBL667794 0.84 PDE4A (0.49) ADORA2AADORA2BPDE4APDE4BPDE4C
SCHEMBL6464905 0.84 PNP (0.35) PNPADORA2AADORA2BPDE4APDE4B
SCHEMBL3671337 0.84 PNP (0.37) PNPADORA2AADORA2BPDE4APDE4B
SCHEMBL669004 0.84 ADORA2B (0.50) PNPADORA2AADORA2BPDE4APDE4B
SCHEMBL5503490 0.83 ADORA2A (0.49) PNPADORA2AADORA2BPDE4APDE4B
SCHEMBL6267115 0.83 ADORA2B (0.48) PNPADORA2AADORA2BPDE4APDE4B
SCHEMBL5048171 0.83 PNP (0.39) PNPADORA2BPDE4APDE4BPDE4C
SCHEMBL6265333 0.82 PDE4A (0.46) PNPADORA2AADORA2BPDE4APDE4B
SCHEMBL8196740 0.82 ADORA2B (0.37) PNPADORA2AADORA2BPDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2468801-B1 PROCESS FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION, MOLDED OBJECT, AND LUMINESCENT OBJECT MITSUBISHI RAYON CO (JP) 2017-04-26 EP disclosed
US-8889785-B2 Production method of thermoplastic resin composition, molded body, and light emission body MITSUBISHI RAYON CO., LTD. (JP) 2014-11-18 US disclosed
US-20120214922-A1 PRODUCTION METHOD OF THERMOPLASTIC RESIN COMPOSITION, MOLDED BODY, AND LIGHT EMISSION BODY MITSUBISHI RAYON CO., LTD. (JP) 2012-08-23 US disclosed
EP-2468801-A1 PROCESS FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION, MOLDED OBJECT, AND LUMINESCENT OBJECT Mitsubishi Rayon Co., Ltd. (JP) 2012-06-27 EP disclosed