SCHEMBL5104179

SCHEMBL5104179

NCCN(CC(=O)O)C(=O)Cn1c(N)nc2[nH]cnc2c1=O

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ HPRT1 P00492 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758685 0.92 PDE4A (0.33) HPRT1
SCHEMBL8343189 0.83 PDE4A (0.35) HPRT1
SCHEMBL5048171 0.81 PNP (0.39) —
SCHEMBL8343186 0.80 HPRT1 (0.31) HPRT1
SCHEMBL7758704 0.76 PDE4A (0.39) —
SCHEMBL6265333 0.75 PDE4A (0.46) —
SCHEMBL5091257 0.75 CYP2C19 (0.30) —
SCHEMBL6265529 0.74 PDE4A (0.34) —
SCHEMBL6267419 0.73 PNP (0.40) —
SCHEMBL6268075 0.72 ADORA2A (0.34) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189941-B1 NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS IPSEN PHARMA (FR) 2013-01-09 — — EP disclosed
US-20080132453-A1 Neuromedin B and somatostatin receptor agonists IPSEN PHARMA S.A.S. (FR) 2008-06-05 — — US disclosed
US-6903074-B1 Neuromedin b and somatostatin receptor agonists SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) 2005-06-07 — — US disclosed
EP-1189941-A1 NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) 2002-03-27 — — EP disclosed
WO-2000075186-A1 NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) 2000-12-14 — — WO disclosed
US-5977296-A MONOMERS WITH ALIPHATIC CYCLIC STRUCTURE IN THE BACKBONE; FOR INCREASED CONFORMATION RESTRICTION LEADING TO INCREASED BINDING AFFINITY AND SPECIFICITY; FOR DETECTING POINT MUTATIONS, FOR SUPPRESSING WILD TYPE GENES IN AMPLIFICATION NIELSEN, PETER E. (DK) 1999-11-02 — — US disclosed
WO-1996020212-A2 PEPTIDE NUCLEIC ACID INCORPORATING A CHIRAL BACKBONE BUCHARDT, DORTE (DK) 1996-07-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132453-A1 Neuromedin B and somatostatin receptor agonists NMBR, NMUR1, NMUR2 HPRT1 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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