Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5104179 | 0.92 | HPRT1 (0.35) | HPRT1 | |
| SCHEMBL7758704 | 0.84 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL5048171 | 0.81 | PNP (0.39) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL8343186 | 0.76 | HPRT1 (0.31) | PDE4APDE4BPDE4CPDE4DHPRT1 | |
| SCHEMBL6265333 | 0.75 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL8594393 | 0.75 | CYP2C19 (0.30) | — | |
| SCHEMBL8343189 | 0.74 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DHPRT1 | |
| SCHEMBL6265529 | 0.74 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL6267419 | 0.73 | PNP (0.40) | PNP | |
| SCHEMBL6268075 | 0.72 | ADORA2A (0.34) | PDE4APDE4BPDE4CPDE4DPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815259-B1 | MODULATION OF THE BINDING PROPERTIES OF NUCLEIC ACID BINDING PARTNERS | PNA DIAGNOSTICS AS (DK) | 2001-05-23 | — | — | EP | disclosed |
| EP-0815259-A1 | MODULATION OF THE BINDING PROPERTIES OF NUCLEIC ACID BINDING PARTNERS | Roche Diagnostics GmbH (DE) | 1998-01-07 | — | — | EP | disclosed |
| EP-0813610-A1 | SEQUENCE-SPECIFIC DETECTION OF NUCLEIC ACIDS | Roche Diagnostics GmbH (DE) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996027680-A1 | SEQUENCE-SPECIFIC DETECTION OF NUCLEIC ACIDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-09-12 | — | — | WO | disclosed |
| WO-1996027679-A1 | MODULATION OF THE BINDING PROPERTIES OF NUCLEIC ACID BINDING PARTNERS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-09-12 | — | — | WO | disclosed |