Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11157593 | 0.84 | TAAR1 (0.57) | TAAR1MAOB | |
| SCHEMBL11272090 | 0.82 | TDP1 (0.53) | MAOB | |
| SCHEMBL19999721 | 0.79 | S1PR1 (0.53) | — | |
| SCHEMBL13554407 | 0.77 | AAK1 (0.45) | MAOB | |
| SCHEMBL12849070 | 0.77 | LTA4H (0.53) | MAOB | |
| SCHEMBL12672292 | 0.76 | TSHR (0.46) | — | |
| SCHEMBL8413209 | 0.76 | TAAR1 (0.47) | TAAR1MAOB | |
| SCHEMBL2693322 | 0.75 | ADRB2 (0.41) | — | |
| SCHEMBL12129217 | 0.75 | CYP2C9 (0.44) | — | |
| SCHEMBL14123467 | 0.74 | TSHR (0.42) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966156-A2 | NEW COMPOUNDS III | AstraZeneca AB (SE) | 2008-09-10 | — | — | EP | claimed |
| WO-2007073303-A2 | NOVEL BENZIMIDAZOLE DERIVATIVES AS VANILLOID RECEPTOR 1 (VRL) INHIBITORS | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | claimed |
| EP-1966156-A2 | NEW COMPOUNDS III | AstraZeneca AB (SE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007073303-A2 | NOVEL BENZIMIDAZOLE DERIVATIVES AS VANILLOID RECEPTOR 1 (VRL) INHIBITORS | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | disclosed |