Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.52 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044016 | 0.91 | MRGPRX4 (0.53) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL5045572 | 0.85 | ALDH1A1 (0.49) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL2358408 | 0.83 | POLB (0.80) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL7220582 | 0.82 | POLB (0.82) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL5048864 | 0.81 | ALDH1A1 (0.62) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL5045562 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL5044168 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL5049250 | 0.79 | SMN1; SMN2 (0.48) | ALDH1A1HDAC3HDAC1NAMPTSMN1; SMN2 | |
| SCHEMBL6359269 | 0.78 | POLB (0.84) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL5048860 | 0.77 | MLYCD (0.53) | ALDH1A1HDAC3HDAC1HDAC2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |