Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.57 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MLYCD | O95822 | 2/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1852697 | 0.92 | MLYCD (0.58) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL5044022 | 0.92 | MRGPRX4 (0.56) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL2358408 | 0.88 | POLB (0.80) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL5044055 | 0.88 | MLYCD (0.51) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL5043673 | 0.88 | ALDH1A1 (0.50) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL7220582 | 0.87 | POLB (0.82) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL1855176 | 0.86 | NAAA (0.68) | HDAC3HDAC1HDAC2SMN1; SMN2MLYCD | |
| SCHEMBL1853372 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 | |
| SCHEMBL27619583 | 0.84 | SMN1; SMN2 (0.58) | HDAC3NAMPTSMN1; SMN2MLYCDNAAA | |
| SCHEMBL5044180 | 0.83 | MRGPRX4 (0.48) | ALDH1A1POLBMRGPRX4TP53BP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |