Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051765 | 0.90 | SLC17A5 (0.58) | SLC17A5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5571166 | 0.85 | SLC17A5 (0.66) | SLC17A5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5276812 | 0.78 | SLC17A5 (0.64) | SLC17A5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5622852 | 0.78 | SLC17A5 (0.64) | SLC17A5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5622471 | 0.78 | SLC17A5 (0.64) | SLC17A5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14456737 | 0.73 | SLC17A5 (0.80) | SLC17A5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5622589 | 0.73 | SLC17A5 (0.80) | SLC17A5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5051764 | 0.72 | MEN1 (0.38) | SLC17A5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14456728 | 0.71 | SLC17A5 (0.68) | SLC17A5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20281115 | 0.71 | SLC17A5 (0.61) | SLC17A5MEN1KMT2AMDM2MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045507-B2 | Coumarin-based amino acids for use in enzyme activity and substrate specificity assays | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-06-02 | — | — | US | disclosed |
| EP-1946102-A1 | COUMARIN-BASED AMINO ACIDS FOR USE IN ENZYME ACTIVITY AND SUBSTRATE SPECIFICITY ASSAYS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-07-23 | — | — | EP | disclosed |
| US-20070031892-A1 | Novel coumarin-based amino acids for use in enzyme activity and substrate specificity assays | USC | 2007-02-08 | — | — | US | disclosed |
| WO-2007014326-A1 | COUMARIN-BASED AMINO ACIDS FOR USE IN ENZYME ACTIVITY AND SUBSTRATE SPECIFICITY ASSAYS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-02-01 | — | — | WO | disclosed |