Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456737 | 0.88 | SLC17A5 (0.80) | SLC17A5MEN1KMT2AEPHX2HSD17B3 | |
| SCHEMBL5622589 | 0.88 | SLC17A5 (0.80) | SLC17A5MEN1KMT2AEPHX2HSD17B3 | |
| SCHEMBL5049234 | 0.85 | SLC17A5 (0.49) | SLC17A5MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14456728 | 0.84 | SLC17A5 (0.68) | SLC17A5MEN1KMT2AEPHX2HSD17B3 | |
| SCHEMBL12647474 | 0.82 | SLC17A5 (0.78) | SLC17A5MEN1KMT2AEPHX2HSD17B3 | |
| SCHEMBL5276812 | 0.78 | SLC17A5 (0.64) | SLC17A5MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5622471 | 0.78 | SLC17A5 (0.64) | SLC17A5MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5622852 | 0.78 | SLC17A5 (0.64) | SLC17A5MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5571171 | 0.77 | SLC17A5 (0.44) | SLC17A5MEN1KMT2AHSD17B3KDM4E | |
| SCHEMBL5050585 | 0.76 | CASP3 (0.53) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045507-B2 | Coumarin-based amino acids for use in enzyme activity and substrate specificity assays | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-06-02 | — | — | US | disclosed |
| US-20070031892-A1 | Novel coumarin-based amino acids for use in enzyme activity and substrate specificity assays | USC | 2007-02-08 | — | — | US | disclosed |