Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051765 | 0.78 | SLC17A5 (0.58) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL5571171 | 0.73 | SLC17A5 (0.44) | MEN1KMT2AKDM4ELCKALDH1A1 | |
| SCHEMBL5049234 | 0.72 | SLC17A5 (0.49) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL30229497 | 0.70 | SDCBP (0.37) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL25179578 | 0.69 | PPARG (0.39) | KMT2AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL30767804 | 0.69 | PPARG (0.39) | KMT2AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL4575653 | 0.69 | MAPT (0.34) | LMNANPSR1POLB | |
| SCHEMBL4600067 | 0.69 | CTRB1 (0.40) | ALDH1A1HTT | |
| SCHEMBL4600752 | 0.69 | CTRB1 (0.40) | ALDH1A1HTT | |
| SCHEMBL30510366 | 0.69 | CTRB1 (0.40) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045507-B2 | Coumarin-based amino acids for use in enzyme activity and substrate specificity assays | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-06-02 | — | — | US | disclosed |
| EP-1946102-A1 | COUMARIN-BASED AMINO ACIDS FOR USE IN ENZYME ACTIVITY AND SUBSTRATE SPECIFICITY ASSAYS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-07-23 | — | — | EP | disclosed |
| US-20070031892-A1 | Novel coumarin-based amino acids for use in enzyme activity and substrate specificity assays | USC | 2007-02-08 | — | — | US | disclosed |
| WO-2007014326-A1 | COUMARIN-BASED AMINO ACIDS FOR USE IN ENZYME ACTIVITY AND SUBSTRATE SPECIFICITY ASSAYS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-02-01 | — | — | WO | disclosed |