SCHEMBL5049243

SCHEMBL5049243

C=C(C)C(=O)OCC(CC)(CC)O[SiH3]

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2229572 0.80 TSHR (0.44) THRBTSHRALDH1A1
SCHEMBL1403767 0.80 TSHR (0.57) THRBTSHRALDH1A1
SCHEMBL1501544 0.80 TSHR (0.53) THRBTSHRALDH1A1
SCHEMBL15955620 0.79 THRB (0.41) THRBTSHRALDH1A1
SCHEMBL2015804 0.79 THRB (0.41) THRBTSHRALDH1A1
SCHEMBL15752920 0.79 THRB (0.41) THRBTSHRALDH1A1
SCHEMBL16286904 0.78 TSHR (0.60) THRBTSHRALDH1A1
SCHEMBL16286642 0.78 TSHR (0.60) THRBTSHRALDH1A1
SCHEMBL5401373 0.78 TSHR (0.41) THRBTSHRALDH1A1
SCHEMBL3075135 0.77 THRB (0.40) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080242766-A1 Curable Composition Containing Surface-Modified Particles CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2008-10-02 US disclosed