SCHEMBL5049269

SCHEMBL5049269

C=C(C)C(=O)OCC=C(C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.46
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
AKT1 P31749 1/20 0.38
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TSHR P16473 1/20 0.37
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27713574 0.87 MTNR1A (0.49) ELANEALDH1A1MAPTTDP1POLB
SCHEMBL9421402 0.84 TDP1 (0.46) ELANEALDH1A1MAPTTDP1POLB
SCHEMBL28775189 0.84 ELANE (0.44) ELANEALDH1A1MAPTTDP1POLB
SCHEMBL27734078 0.84 ELANE (0.44) ELANEALDH1A1MAPTTDP1POLB
SCHEMBL29827845 0.83 ALDH1A1 (0.48) ELANEALDH1A1TDP1AKT1MTNR1A
SCHEMBL20557153 0.83 AKT1 (0.42) ALDH1A1TDP1AKT1MTNR1AMTNR1B
SCHEMBL20557152 0.83 MTNR1A (0.46) ALDH1A1TDP1AKT1MTNR1AMTNR1B
SCHEMBL20557151 0.83 MTNR1A (0.46) ALDH1A1TDP1AKT1MTNR1AMTNR1B
SCHEMBL21119365 0.79 MTNR1A (0.46) AKT1MTNR1AMTNR1BLMNATSHR
SCHEMBL21119244 0.79 MTNR1A (0.46) AKT1MTNR1AMTNR1BLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110352212-B Biaxially stretched acrylic resin film and method for producing same 株式会社可乐丽 2022-04-01 CN disclosed
WO-2021117903-A1 METHACRYLIC COPOLYMER AND MANUFACTURING METHOD SUITABLE FOR MANUFACTURING SAME 株式会社クラレ 2021-06-17 WO disclosed
US-20080020466-A1 Detection Method Using Detecting Device BML, INC. (JP) 2008-01-24 US disclosed
US-20050213906-A1 Optical transmission mediums, and processes and apparatus for producing optical transmission mediums FUJIFILM CORPORATION (JP) 2005-09-29 US disclosed
US-20050118584-A1 Detection board BML, INC. (JP) 2005-06-02 US disclosed
EP-1342753-B1 Flame retardant resine compositions and molded articles SHINETSU CHEMICAL CO (JP) 2005-01-26 EP disclosed
EP-1452866-A1 SENSING BOARD BML, Inc. (JP) 2004-09-01 EP disclosed
US-6706825-B2 BLEND OF A POLYPHENYLSILOXANE AND NONAROMATIC GROUP-CONTAINING POLYSILOXANE; AROMATIC POLYCARBONATE, AND THEMOPLASTIC RESIN; ELECTRONICS, AUTOMOBILES; ENGINEERING THERMOPLASTICS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-03-16 US disclosed
US-20030199631-A1 Flame retardant resin compositions and molded articles SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-10-23 US disclosed
EP-1342753-A1 Flame retardant resine compositions and molded articles SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-09-10 EP disclosed
US-4448580-A Process for producing α-methyl styrene-methyl methacrylate-acrylonitrile thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1984-05-15 US disclosed
US-4306043-A A-METHYLSTYRENE, METHYL METHACRYLATE, ACRYLONITRILE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-12-15 US disclosed