Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557152 | 1.00 | MTNR1A (0.46) | MTNR1AMTNR1BAKT1LMNACYP1A2 | |
| SCHEMBL21119365 | 0.91 | MTNR1A (0.46) | MTNR1AMTNR1BAKT1LMNAPPARG | |
| SCHEMBL21119244 | 0.91 | MTNR1A (0.46) | MTNR1AMTNR1BAKT1LMNAPPARG | |
| SCHEMBL29827845 | 0.89 | ALDH1A1 (0.48) | MTNR1AMTNR1BAKT1LMNACYP1A2 | |
| SCHEMBL20557153 | 0.89 | AKT1 (0.42) | MTNR1AMTNR1BAKT1LMNACYP1A2 | |
| SCHEMBL5049269 | 0.83 | ELANE (0.46) | MTNR1AMTNR1BAKT1LMNACYP1A2 | |
| SCHEMBL27567294 | 0.83 | TRPV1 (0.42) | MTNR1AMTNR1BAKT1LMNACYP1A2 | |
| SCHEMBL7259155 | 0.83 | TRPV1 (0.42) | MTNR1AMTNR1BAKT1LMNACYP1A2 | |
| SCHEMBL7804762 | 0.82 | MTNR1A (0.44) | MTNR1AMTNR1BLMNACYP1A2CYP2D6 | |
| SCHEMBL20557155 | 0.80 | SMN1; SMN2 (0.49) | HSD17B10CES2CES1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336678-B2 | Compositions and methods for preparing β,γ-unsaturated acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180327343-A1 | COMPOSITIONS AND METHODS FOR PREPARING BETA,GAMMA-UNSATURATED ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2018-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336678-B2 | Compositions and methods for preparing β,γ-unsaturated acids | ELOVL5, FASN, ACSL5 | MTNR1A 4307/4885MTNR1B 4333/4885AKT1 1306/4885 |
| US-20180327343-A1 | COMPOSITIONS AND METHODS FOR PREPARING BETA,GAMMA-UNSATURATED ACIDS | ELOVL5, FASN, ACSL5 | MTNR1A 4113/4885MTNR1B 4017/4885AKT1 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.