Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049373 | 0.79 | CNR1 (0.44) | CNR1DPP4CNR2HSD11B1 | |
| SCHEMBL5051902 | 0.76 | TSHR (0.54) | HSD11B1 | |
| SCHEMBL13307799 | 0.71 | CNR1 (0.89) | CNR1CNR2 | |
| SCHEMBL5051915 | 0.70 | CNR1 (0.55) | CNR1DPP4HSD11B1CRHR1 | |
| SCHEMBL3611261 | 0.68 | CNR1 (0.50) | CNR1DPP4CNR2CRHR1 | |
| SCHEMBL1045006 | 0.67 | AHR (0.57) | DPP4HSD11B1 | |
| SCHEMBL3599456 | 0.67 | SIGMAR1 (0.44) | CNR1CNR2 | |
| SCHEMBL13307817 | 0.66 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL8031277 | 0.60 | HSD11B1 (0.47) | HSD11B1CRHR1 | |
| SCHEMBL11487466 | 0.59 | NPC1 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |