Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031860 | 0.86 | HSD11B1 (0.40) | HSD11B1CRHR1 | |
| SCHEMBL17290439 | 0.79 | HSD11B1 (0.50) | HSD11B1CRHR1NPC1 | |
| SCHEMBL9864465 | 0.76 | HSD11B1 (0.50) | HSD11B1CRHR1 | |
| SCHEMBL9496647 | 0.76 | CNR1 (0.46) | HSD11B1CRHR1 | |
| SCHEMBL14996580 | 0.75 | HSD11B1 (0.53) | HSD11B1CRHR1NPC1 | |
| SCHEMBL8031897 | 0.74 | HSD11B1 (0.45) | HSD11B1CRHR1 | |
| SCHEMBL8626557 | 0.72 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL8022013 | 0.72 | POLB (0.32) | — | |
| SCHEMBL14996667 | 0.72 | HSD11B1 (0.53) | HSD11B1CRHR1 | |
| SCHEMBL14996575 | 0.72 | HSD11B1 (0.53) | HSD11B1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103667-A | Phenylpyrazole herbicides | NOVARTIS CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0832070-A1 | NOVEL HERBICIDES | Novartis AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997000246-A1 | NOVEL HERBICIDES | NOVARTIS AG (CH) | 1997-01-03 | — | — | WO | disclosed |