SCHEMBL5049482

SCHEMBL5049482

CCNC(=O)C(c1ccccc1)C1CCCCC1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.63
CYP3A4 P08684 2/20 0.63
CYP2D6 P10635 2/20 0.63
TSHR P16473 2/20 0.63
TP53 P04637 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
HTR1E P28566 2/20 0.62
S1PR3 Q99500 2/20 0.62
LMNA P02545 2/20 0.62
MEN1 O00255 1/20 0.62
MAPT P10636 1/20 0.62
KMT2A Q03164 1/20 0.62
CHRM2 P08172 1/20 0.54
HTR1A P08908 1/20 0.54
ADRA2A P08913 1/20 0.54
CHRM1 P11229 1/20 0.54
DRD1 P21728 1/20 0.54
SLC6A2 P23975 1/20 0.54
ADRA1A P35348 1/20 0.54
OPRM1 P35372 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5049558 0.98 HTR1E (0.64) CYP1A2CYP3A4CYP2D6TSHRTP53
SCHEMBL5080882 0.86 SMYD3 (0.50) CYP1A2CYP3A4CYP2D6TSHRTP53
SCHEMBL9829773 0.84 HTR1E (0.64) CYP1A2CYP3A4CYP2D6TSHRTP53
SCHEMBL5077966 0.83 KDM4E (0.53) CYP1A2CYP3A4CYP2D6TSHRTP53
SCHEMBL13923636 0.81 HTR1E (0.74) CYP1A2CYP3A4CYP2D6TSHRTP53
SCHEMBL2844637 0.81 HTR1E (0.69) CYP1A2CYP3A4CYP2D6TSHRTP53
SCHEMBL4866353 0.81 CYP3A4 (0.63) CYP1A2CYP3A4CYP2D6TSHRTP53
SCHEMBL4877735 0.80 CYP3A4 (0.64) CYP1A2CYP3A4CYP2D6TSHRTP53
SCHEMBL13305279 0.80 HTR1E (0.67) CYP1A2CYP3A4CYP2D6TSHRTP53
SCHEMBL4874880 0.80 TP53 (0.70) CYP1A2CYP3A4CYP2D6TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948164-A1 PHARMACEUTICAL COMPOSITIONS OF MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES, LTD. (IN) 2008-07-30 EP claimed
WO-2007045979-A1 PHARMACEUTICAL COMPOSITIONS OF MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2007-04-26 WO claimed