Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1E | P28566 | 3/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049482 | 0.98 | CYP1A2 (0.63) | HTR1ES1PR3MEN1LMNAKMT2A | |
| SCHEMBL5080882 | 0.87 | SMYD3 (0.50) | HTR1ES1PR3MEN1LMNAKMT2A | |
| SCHEMBL9829773 | 0.85 | HTR1E (0.64) | HTR1ES1PR3MEN1LMNAKMT2A | |
| SCHEMBL5077966 | 0.85 | KDM4E (0.53) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL13923636 | 0.83 | HTR1E (0.74) | HTR1ES1PR3MEN1LMNAKMT2A | |
| SCHEMBL4866353 | 0.83 | CYP3A4 (0.63) | HTR1ES1PR3MEN1LMNAKMT2A | |
| SCHEMBL4877735 | 0.82 | CYP3A4 (0.64) | HTR1ES1PR3MEN1LMNAKMT2A | |
| SCHEMBL13305279 | 0.81 | HTR1E (0.67) | HTR1ES1PR3MEN1LMNAKMT2A | |
| SCHEMBL5049447 | 0.81 | HTR1E (0.71) | HTR1ES1PR3MEN1LMNAKMT2A | |
| SCHEMBL22899817 | 0.81 | TSHR (0.63) | HTR1ES1PR3MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948164-A1 | PHARMACEUTICAL COMPOSITIONS OF MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2008-07-30 | — | — | EP | claimed |
| WO-2007045979-A1 | PHARMACEUTICAL COMPOSITIONS OF MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | claimed |