SCHEMBL50495

SCHEMBL50495

CC(=O)N(C)CCC#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21680771 0.81
SCHEMBL3558943 0.81
SCHEMBL3810193 0.79
SCHEMBL22922461 0.79
SCHEMBL6631976 0.79
SCHEMBL8801226 0.79
Acetic Acid SCHEMBL9547276 0.79 CASP1 (0.44)
SCHEMBL491081 0.79 CASP1 (0.44)
SCHEMBL1344184 0.78 ALDH1A1 (0.44)
SCHEMBL14098259 0.77 CASP1 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106401868-B A kind of pedestal vertical axis angle variable wind generator system and its working method 徐州工程学院 2019-04-05 CN claimed
CN-106195624-B A kind of large-scale liquefied natural gas vaporizing apparatus of cell and its method of work 徐州工程学院 2018-04-03 CN claimed
CN-106401868-A Support type vertical-axis variable-angle wind power generation system and operating method thereof 徐州工程学院 2017-02-15 CN claimed
CN-106195624-A A kind of large-scale liquefied natural gas vaporizing apparatus in community and method of work thereof 徐州工程学院 2016-12-07 CN claimed
EP-0127827-B1 PROCESS FOR PREPARING CHLOROPYRIMIDINES BAYER AG (DE) 1990-01-24 EP claimed
EP-4630410-A1 POLQ INHIBITORS Astrazeneca AB (SE) 2025-10-15 EP disclosed
WO-2024121753-A1 POLQ INHIBITORS ASTRAZENECA AB (SE) 2024-06-13 WO disclosed
CN-114507244-B Imidazo thiazole compound, pharmaceutical composition and application thereof 广州市恒诺康医药科技有限公司 2023-10-27 CN disclosed
WO-2022100727-A1 IMIDAZOTHIAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF 广州市恒诺康医药科技有限公司 2022-05-19 WO disclosed
CN-114507244-A Imidazothiazole compounds, pharmaceutical compositions thereof and uses thereof 广州市恒诺康医药科技有限公司 2022-05-17 CN disclosed
EP-3526218-B1 HETEROCYCLIC SULFONES AS ROR GAMMA MODULATORS BRISTOL MYERS SQUIBB CO (US) 2021-04-21 EP disclosed
CN-106401868-B A kind of pedestal vertical axis angle variable wind generator system and its working method 徐州工程学院 2019-04-05 CN disclosed
US-7332492-B2 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2008-02-19 US disclosed
US-7332492-B2 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2008-02-19 US disclosed
EP-1317459-B1 BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS ASTRAZENECA AB (SE) 2004-04-07 EP disclosed
US-20030232875-A1 Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors ASTRAZENECA AB (SE) 2003-12-18 US disclosed
EP-1317459-A1 BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS AstraZeneca AB (SE) 2003-06-11 EP disclosed
WO-2002020530-A1 BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS ASTRAZENECA AB (SE) 2002-03-14 WO disclosed
EP-0127827-B1 PROCESS FOR PREPARING CHLOROPYRIMIDINES BAYER AG (DE) 1990-01-24 EP disclosed
EP-0127827-A2 Process for preparing chloropyrimidines BAYER AG (DE) 1984-12-12 EP disclosed