SCHEMBL491081

SCHEMBL491081

C=C(C)C(=O)N(C)CCC#N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.44
ALDH1A1 P00352 11/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
DPP4 P27487 1/20 0.34
KDM4E B2RXH2 4/20 0.33
KMT2A Q03164 3/20 0.33
CYP1A2 P05177 2/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 2/20 0.33
GLA P06280 1/20 0.33
NPC1 O15118 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
RAB9A P51151 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL474981 0.82 ALDH1A1 (0.40) CASP1ALDH1A1HTTMAPTHPGD
SCHEMBL9814628 0.80 TDP1 (0.36) ALDH1A1
SCHEMBL3409712 0.79 DPP4 (0.48) DPP4CYP1A2
SCHEMBL50495 0.79
SCHEMBL15730987 0.79
SCHEMBL8699021 0.77 CYP1A2 (0.39) CASP1ALDH1A1HTTHPGDKMT2A
SCHEMBL2813504 0.77 MLYCD (0.43) CASP1ALDH1A1HTTMAPTHPGD
SCHEMBL6631976 0.77
SCHEMBL9906112 0.76 TDP1 (0.33)
SCHEMBL2817304 0.76 MLYCD (0.36) CASP1ALDH1A1HTTHPGDDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8603709-B2 Polyurethane anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2013-12-10 US claimed
EP-2224288-B1 PHOTOCONDUCTORS COMPRISING EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER XEROX CORP (US) 2013-10-16 EP claimed
US-8105670-B2 Glycoluril resin and polyol resin dual members XEROX CORPORATION (US) 2012-01-31 US claimed
US-20110318679-A1 POLYURETHANE ANTICURL BACKSIDE COATING (ACBC) PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-12-29 US claimed
US-8084110-B2 Glycoluril resin and polyol resin members XEROX CORPORATION (US) 2011-12-27 US claimed
US-8067139-B2 Resin mixture backing layer containing photoconductor XEROX CORPORATION (US) 2011-11-29 US claimed
EP-2237114-A1 Glycoluril resin and polyol resin members Xerox Corporation (US) 2010-10-06 EP claimed
EP-2237115-A1 Intermediate transfer member comprising a coating of a mxiture of glycoluril resin and polyol resin Xerox Corporation (US) 2010-10-06 EP claimed
US-20100248108-A1 GLYCOLURIL RESIN AND POLYOL RESIN DUAL MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100248107-A1 GLYCOLURIL RESIN AND POLYOL RESIN MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100248103-A1 RESIN MIXTURE BACKING LAYER CONTAINING PHOTOCONDUCTOR XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100221651-A1 EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2010-09-02 US claimed
EP-2224288-A2 Epoxy carboxyl resin mixture hole blocking layer photoconductors Xerox Corporation (US) 2010-09-01 EP claimed
US-7579126-B2 Hole blocking layer containing photoconductors XEROX CORPORATION (US) 2009-08-25 US claimed
US-20080220350-A1 Hole blocking layer containing photoconductors XEROX CORPORATION 2008-09-11 US claimed
EP-1967907-A1 Hole Blocking Layer Containing Photoconductors Xerox Corporation (US) 2008-09-10 EP claimed
US-20070248813-A1 Imaging member having styrene XEROX CORPORATION (US) 2007-10-25 US claimed
US-20190270857-A1 PLANARIZATION COATING FOR FLEXIBLE PRINTED ELECTRONICS XEROX CORPORATION (US) 2019-09-05 US disclosed
US-5318852-A Fine particles of crosslinked vinyl polymer and process for producing the same KAO CORPORATION (JP) 1994-06-07 US disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed