⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276778 | 1.00 | — | — | |
| SCHEMBL13366391 | 1.00 | — | — | |
| Ethane SCHEMBL8514870 | 0.97 | CA1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL10336374 | 0.97 | — | — | |
| SCHEMBL3392036 | 0.85 | ALDH1A1 (0.38) | — | |
| SCHEMBL19619339 | 0.80 | CA1 (0.37) | — | |
| SCHEMBL11413659 | 0.80 | ECE1 (0.35) | — | |
| Acetamide SCHEMBL4103797 | 0.80 | LMNA (0.47) | — | |
| SCHEMBL25078569 | 0.79 | — | — | |
| SCHEMBL276380 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338588-A1 | Granzyme B Directed Imaging and Therapy | THE GENERAL HOSPITAL CORPORATION | 2023-10-26 | — | — | US | disclosed |
| US-20230312650-A1 | Antifungal Peptides, Compounds Including The Same, And Methods Of Use Thereof | SETON HALL UNIVERSITY (US) | 2023-10-05 | — | — | US | disclosed |
| CN-111454436-B | Preparation method of chiral conjugated microporous polymer containing (S) -N-sec-butylacetamide | 齐齐哈尔大学 | 2022-12-20 | — | — | CN | disclosed |
| US-20170290878-A1 | METHODS OF TREATING CANCER WITH TUBULYSIN CONJUGATES | ENDOCYTE INC (US) | 2017-10-12 | — | — | US | disclosed |
| WO-2017175233-A1 | PROCESS FOR LARGE SCALE LIQUID PHASE SYNTHESIS OF CARBETOCIN AND ITS NOVEL INTERMEDIATES | DAVULURI RAMAMOHAN RAO (IN) | 2017-10-12 | — | — | WO | disclosed |
| US-20120041019-A1 | PROTEASE INHIBITORS | AMPLYX PHARMACEUTICALS, INC. | 2012-02-16 | — | — | US | disclosed |
| WO-2010053546-A2 | CRF1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053545-A2 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| US-7375127-B2 | Tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCRs) | AE ZENTARIS GMBH (DE) | 2008-05-20 | — | — | US | disclosed |
| US-20060014818-A1 | Novel tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCRs) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2006-01-19 | — | — | US | disclosed |
| EP-0954526-A2 | SERINE PROTEASE INHIBITORS | CORTECH, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998024806-A2 | SUBSTITUTED OXADIAZOLE, THIADIAZOLE AND TRIAZOLE SERINE PROTEASE INHIBITORS | CORTECH, INC. (US) | 1998-06-11 | — | — | WO | disclosed |