Ethane

Ethane

SCHEMBL8514870

CC.CCC(C)CC(N)=O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
ECE1 P42892 4/20 0.33
ELANE P08246 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 1/20 0.32
ALOX15 P16050 2/20 0.31
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
GLA P06280 1/20 0.30
POLB P06746 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13366391 0.97
SCHEMBL276778 0.97
SCHEMBL5049546 0.97
Hydrochloric Acid SCHEMBL10336374 0.95
SCHEMBL3392036 0.83 ALDH1A1 (0.38) CA2ECE1ALDH1A1TDP1TSHR
SCHEMBL19619339 0.78 CA1 (0.37) CA1CA2CA7CA14ECE1
SCHEMBL11413659 0.78 ECE1 (0.35) CA2ECE1ALDH1A1TDP1ALOX15
Acetamide SCHEMBL4103797 0.78 LMNA (0.47) CA2ECE1ALDH1A1TDP1ALOX15
SCHEMBL25078569 0.77
SCHEMBL276380 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250057798-A1 THERAPEUTIC USE OF COMPOUNDS UCL BUSINESS LTD (GB) 2025-02-20 US disclosed
US-12090131-B2 Therapeutic use of compounds UCL BUSINESS LTD (GB) 2024-09-17 US disclosed
US-20230146709-A1 THERAPEUTIC USE OF COMPOUNDS UCL BUSINESS LTD (GB) 2023-05-11 US disclosed
US-11491127-B2 Therapeutic use of compounds UCL BUSINESS PLC (GB) 2022-11-08 US disclosed
US-11419839-B2 Therapeutic use of compounds UCL BUSINESS LTD (GB) 2022-08-23 US disclosed
EP-2737901-B1 Therapeutic Use of Compounds UCL BUSINESS LTD (GB) 2021-03-03 EP disclosed
US-20200268699-A1 THERAPEUTIC USE OF COMPOUNDS UCL BUSINESS LTD (GB) 2020-08-27 US disclosed
US-20200197344-A1 THERAPEUTIC USE OF COMPOUNDS UCL BUSINESS LTD (GB) 2020-06-25 US disclosed
EP-3636259-A1 THERAPEUTIC USE OF COMPOUNDS UCL BUSINESS LTD (GB) 2020-04-15 EP disclosed
US-10548866-B2 Therapeutic use of compounds UCL BUSINESS LTD (GB) 2020-02-04 US disclosed
EP-2642990-B1 THERAPEUTIC USE OF COMPOUNDS UCL BUSINESS PLC (GB) 2019-09-18 EP disclosed
EP-2737901-A1 Therapeutic Use of Compounds UCL Business PLC (GB) 2014-06-04 EP disclosed
US-20130303616-A1 THERAPEUTIC USE OF COMPOUNDS UCL BUSINESS PLC (GB) 2013-11-14 US disclosed
EP-2642990-A1 THERAPEUTIC USE OF COMPOUNDS UCL Business Plc. (GB) 2013-10-02 EP disclosed
WO-2012069790-A1 THERAPEUTIC USE OF COMPOUNDS ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) 2012-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146709-A1 THERAPEUTIC USE OF COMPOUNDS SGMS1, CHRM1, CYP11B1 CA1 1504/4885CA2 2395/4885CA7 862/4885
US-20200268699-A1 THERAPEUTIC USE OF COMPOUNDS DEGS1, CYP11B1, SGMS1 CA1 1687/4885CA2 2879/4885CA7 1072/4885
US-20130303616-A1 THERAPEUTIC USE OF COMPOUNDS BACE1, CPT1A, BCL6 CA1 1559/4885CA2 3274/4885CA7 3452/4885
US-10548866-B2 Therapeutic use of compounds BACE1, BCL6, BCL6B CA1 1581/4885CA2 2995/4885CA7 3131/4885
US-20250057798-A1 THERAPEUTIC USE OF COMPOUNDS CYP11B1, SGMS1, PTGER1 CA1 1286/4885CA2 2311/4885CA7 965/4885
US-12090131-B2 Therapeutic use of compounds SGMS1, CHRM1, CYP11B1 CA1 1504/4885CA2 2395/4885CA7 862/4885
US-11419839-B2 Therapeutic use of compounds SGMS1, CHRM1, CYP11B1 CA1 1504/4885CA2 2395/4885CA7 862/4885
US-11491127-B2 Therapeutic use of compounds SGMS1, CHRM1, CYP11B1 CA1 1504/4885CA2 2395/4885CA7 862/4885
US-20200197344-A1 THERAPEUTIC USE OF COMPOUNDS SGMS1, CHRM1, CYP11B1 CA1 1504/4885CA2 2395/4885CA7 862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.