Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13510718 | 0.82 | CASP3 (0.43) | WDR5MAPTCHRM2CHRM3KDM4E | |
| SCHEMBL5049416 | 0.75 | CHRM2 (0.43) | MAPTCHRM2CHRM3KDM4ENPC1 | |
| SCHEMBL18590273 | 0.72 | ALDH1A1 (0.42) | MAPTTP53CHRM2CHRM3KDM4E | |
| SCHEMBL5049564 | 0.72 | MEN1 (0.49) | WDR5MAPTTP53CYP1A2NPC1 | |
| SCHEMBL18598425 | 0.71 | CHRM2 (0.40) | TP53CHRM2CHRM3ALDH1A1 | |
| SCHEMBL10332011 | 0.69 | SMN1; SMN2 (0.54) | MAPTTP53CYP1A2MCL1NPC1 | |
| SCHEMBL197284 | 0.69 | ALDH1A3 (0.56) | CYP1A2MCL1ALDH1A1NOTUMMAP4K4 | |
| SCHEMBL13509095 | 0.68 | TDP1 (0.43) | WDR5MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL5047941 | 0.67 | TLR8 (0.54) | WDR5MAPTCYP1A2KDM4ENPC1 | |
| SCHEMBL125543 | 0.66 | ALDH1A3 (0.64) | TP53CYP1A2ALDH1A1NOTUMALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |