Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 7/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.60 |
| ▸ | PRKACA | P17612 | 5/20 | 0.60 |
| ▸ | CDK2 | P24941 | 5/20 | 0.60 |
| ▸ | GSK3B | P49841 | 5/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.60 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.60 |
| ▸ | PIM1 | P11309 | 3/20 | 0.60 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.57 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.57 |
| ▸ | FLT3 | P36888 | 3/20 | 0.57 |
| ▸ | CLK2 | P49760 | 3/20 | 0.57 |
| ▸ | PRKX | P51817 | 3/20 | 0.57 |
| ▸ | JAK3 | P52333 | 3/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.57 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.57 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051897 | 1.00 | CDC7 (0.60) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL2898117 | 0.92 | IDO1 (0.65) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL5051921 | 0.90 | TDO2 (0.54) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL5050336 | 0.90 | TDO2 (0.54) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL5047920 | 0.79 | SLC9A1 (0.49) | CYP19A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL5053635 | 0.79 | SLC9A1 (0.49) | CYP19A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL5049432 | 0.78 | SLC9A1 (0.50) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5049522 | 0.78 | SLC9A1 (0.50) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3637386 | 0.77 | CDC7 (0.55) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL28340574 | 0.75 | CDC7 (0.64) | CDC7MAP4K4PRKACACDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |