Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.54 |
| ▸ | CDC7 | O00311 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | PRKACA | P17612 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051921 | 1.00 | TDO2 (0.54) | TDO2CDC7MAP4K4PIM1PRKACA | |
| SCHEMBL5049567 | 0.90 | CDC7 (0.60) | TDO2CDC7MAP4K4PIM1PRKACA | |
| SCHEMBL5051897 | 0.90 | CDC7 (0.60) | TDO2CDC7MAP4K4PIM1PRKACA | |
| SCHEMBL28000406 | 0.83 | TDO2 (0.53) | TDO2CDC7MAP4K4PIM1PRKACA | |
| SCHEMBL2898117 | 0.83 | IDO1 (0.65) | TDO2CDC7MAP4K4PIM1PRKACA | |
| SCHEMBL28326488 | 0.79 | CYP19A1 (0.43) | TDO2CDC7MAP4K4PIM1PRKACA | |
| SCHEMBL5047930 | 0.77 | MEN1 (0.52) | CDK2AURKAMAPK1MEN1HTT | |
| SCHEMBL5053635 | 0.74 | SLC9A1 (0.49) | CYP19A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL5047920 | 0.74 | SLC9A1 (0.49) | CYP19A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL28000407 | 0.73 | TDO2 (0.51) | TDO2CDC7MAP4K4PIM1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |