Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9933562 | 0.81 | GABRA1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL7201334 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2GABRB1LMNAHPGD | |
| SCHEMBL8134144 | 0.75 | GABRA1 (0.42) | GABRA1GABRB2GABRB1PDE4APDE4B | |
| SCHEMBL7070227 | 0.75 | BRD4 (0.36) | LMNAHTTMAPTTP53HPGD | |
| SCHEMBL7066663 | 0.74 | GABRA1 (0.35) | GABRA1GABRB2HPGD | |
| SCHEMBL15833732 | 0.73 | GABRA1 (0.48) | GABRA1GABRB2GABRB1PDE4APDE4B | |
| SCHEMBL891578 | 0.72 | LMNA (0.36) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL15757985 | 0.71 | ALDH1A1 (0.37) | LMNAHTTMAPT | |
| SCHEMBL8112261 | 0.71 | CYP2A6 (0.37) | LMNAHTTMAPTTSHR | |
| SCHEMBL15757626 | 0.71 | LMNA (0.34) | LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981898-A2 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZOÝ1,2-f¨PHENANTHRIDINE AND DIIMIDAZOÝ1,2-A:1',2'-C¨QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | Universal Display Corporation (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007095118-A2 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f]PHENANTHRIDINE AND DIIMIDAZO[1,2-A:1',2'-C]QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | UNIVERSAL DISPLAY CORPORATION (US) | 2007-08-23 | — | — | WO | claimed |