Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283339 | 0.86 | KCNH2 (0.50) | SIGMAR1KCNH2SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9084597 | 0.81 | SMN1; SMN2 (0.61) | SIGMAR1SMN1; SMN2ALDH1A1CYP3A4IDO1 | |
| SCHEMBL21799747 | 0.79 | SIGMAR1 (0.46) | SIGMAR1KCNH2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10547652 | 0.79 | TAAR1 (0.45) | ALDH1A1LMNACYP3A4TSHRSLC6A2 | |
| SCHEMBL12637135 | 0.79 | HTR2A (0.48) | ALDH1A1LMNACYP3A4TSHRRAB9A | |
| SCHEMBL22810528 | 0.79 | TAAR1 (0.45) | KCNH2CYP3A4HTR1AADRA2ATSHR | |
| SCHEMBL1872028 | 0.79 | TAAR1 (0.47) | SIGMAR1LMNACYP2D6SLC6A2ADRA1A | |
| SCHEMBL1878622 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1ATML3MBTL1EPHX2 | |
| SCHEMBL21799461 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNATAAR1HTR2AMAPT | |
| SCHEMBL21799774 | 0.76 | CYP3A4 (0.49) | KCNH2SMN1; SMN2ALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819505-A4 | POLYESTER/POLYAMIDE BLEND HAVING IMPROVED FLAVOR RETAINING PROPERTY AND CLARITY | EASTMAN CHEM CO (US) | 2008-09-24 | — | — | EP | disclosed |
| US-7375154-B2 | Polyester/polyamide blend having improved flavor retaining property and clarity | EASTMAN CHEMICAL COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1819505-A2 | POLYESTER/POLYAMIDE BLEND HAVING IMPROVED FLAVOR RETAINING PROPERTY AND CLARITY | EASTMAN CHEMICAL COMPANY (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006062749-A2 | POLYESTER/POLYAMIDE BLEND HAVING IMPROVED FLAVOR RETAINING PROPERTY AND CLARITY | EASTMAN CHEMICAL COMPANY (US) | 2006-06-15 | — | — | WO | disclosed |
| US-20060122306-A1 | Polyester/polyamide blend having improved flavor retaining property and clarity | EASTMAN CHEMICAL COMPANY | 2006-06-08 | — | — | US | disclosed |