Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049798 | 0.86 | SIGMAR1 (0.49) | KCNH2SIGMAR1SMN1; SMN2ALDH1A1MAOA | |
| SCHEMBL12637361 | 0.82 | HRH1 (0.52) | KCNH2HRH1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20725540 | 0.80 | KCNH2 (0.44) | KCNH2SIGMAR1SMN1; SMN2ALDH1A1MAOA | |
| SCHEMBL8135255 | 0.77 | HRH1 (0.52) | KCNH2HRH1SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17821183 | 0.75 | ALDH1A1 (0.49) | SIGMAR1SMN1; SMN2ALDH1A1MAOANPC1 | |
| SCHEMBL4915574 | 0.75 | L3MBTL1 (0.51) | KCNH2HRH1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL1878622 | 0.75 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1ATMEPHX2 | |
| SCHEMBL11203104 | 0.74 | HRH1 (0.54) | HRH1SMN1; SMN2LMNACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10782582 | 0.74 | L3MBTL1 (0.50) | KCNH2HRH1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL7616722 | 0.74 | RAB9A (0.71) | KCNH2SIGMAR1SMN1; SMN2ALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006544-A2 | CYCLIC ADENOSINE MONOPHOSPHATE COMPOUNDS FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2007-01-18 | — | — | WO | claimed |
| WO-2007006544-A2 | CYCLIC ADENOSINE MONOPHOSPHATE COMPOUNDS FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2007-01-18 | — | — | WO | disclosed |