Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789063 | 0.87 | MAPT (0.52) | TDP1ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL3783410 | 0.85 | AAK1 (0.44) | TDP1ALDH1A1CYP3A4TP53MEN1 | |
| SCHEMBL3781489 | 0.84 | MAOA (0.46) | ALDH1A1CYP3A4TP53MEN1KMT2A | |
| SCHEMBL3787008 | 0.79 | TDP1 (0.46) | TDP1ALDH1A1CYP3A4TP53MEN1 | |
| SCHEMBL3787049 | 0.78 | TDP1 (0.36) | TDP1ALDH1A1CYP3A4TP53MEN1 | |
| SCHEMBL3789358 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL16528615 | 0.77 | SLC6A2 (0.50) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL3791267 | 0.75 | MEN1 (0.35) | TDP1ALDH1A1CYP3A4TP53MEN1 | |
| SCHEMBL3781267 | 0.75 | SLC6A2 (0.51) | TDP1ALDH1A1CYP3A4TP53KMT2A | |
| SCHEMBL3789854 | 0.74 | HTR7 (0.46) | TDP1ALDH1A1CYP3A4TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |