Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 17/20 | 0.43 |
| ▸ | MEN1 | O00255 | 12/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 9/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048583 | 0.82 | GAA (0.47) | GAAMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL8174947 | 0.81 | FAAH (0.51) | ALDH1A1HPGDUSP2POLBKDM4E | |
| SCHEMBL399012 | 0.78 | GAA (0.50) | GAAMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL8174534 | 0.76 | TSHR (0.46) | GAAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL25384603 | 0.73 | FAAH (0.62) | ALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL5049959 | 0.73 | BCL2 (0.40) | KMT2AALDH1A1HTTCYP2C9CYP2C19 | |
| SCHEMBL5049958 | 0.70 | GHSR (0.35) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8348221 | 0.69 | FAAH (0.46) | GAAKMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL16512497 | 0.69 | FAAH (0.51) | — | |
| SCHEMBL2934983 | 0.69 | FAAH (0.46) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207528-A1 | Administering derivatives of 4-(3-pyrrolidinyloxy)quinoline | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207528-A1 | Administering derivatives of 4-(3-pyrrolidinyloxy)quinoline | GLS2, SLC10A1, UGT1A1 | GAA 846/4885MEN1 2832/4885KMT2A 3331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.