Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344329 | 0.86 | KMT2A (0.50) | FAAHKMT2ATRPV1GHSRTDP1 | |
| SCHEMBL8345080 | 0.85 | MEN1 (0.52) | FAAHKMT2ATRPV1GHSRTDP1 | |
| SCHEMBL8346749 | 0.82 | GHSR (0.47) | FAAHKMT2ATRPV1GHSRPOLB | |
| SCHEMBL8347084 | 0.80 | FAAH (0.57) | FAAHTRPV1GHSR | |
| SCHEMBL8334553 | 0.79 | FAAH (0.56) | FAAHTRPV1GHSRGAATSHR | |
| SCHEMBL25384603 | 0.79 | FAAH (0.62) | FAAHTRPV1GHSRPOLBALDH1A1 | |
| SCHEMBL24574915 | 0.77 | LCK (0.60) | KMT2ALCKPOLBALDH1A1TSHR | |
| SCHEMBL6268190 | 0.77 | FAAH (0.63) | FAAHTRPV1GHSR | |
| SCHEMBL2934983 | 0.77 | FAAH (0.46) | FAAHTRPV1GHSRPOLB | |
| SCHEMBL6239518 | 0.76 | FAAH (0.65) | FAAHTRPV1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |