Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58882 | 0.81 | TDP1 (0.44) | CYP19A1ALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL9746065 | 0.80 | ELANE (0.45) | CYP19A1ALDH1A1MAPK1TRPA1GSK3B | |
| Diphenyl Ethanedioat SCHEMBL43364 | 0.79 | TDP1 (0.54) | CYP19A1ALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL27491574 | 0.79 | TDP1 (0.42) | CYP19A1ALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL11033789 | 0.79 | TDP1 (0.42) | CYP19A1ALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL237447 | 0.79 | CES2 (0.50) | CYP19A1ALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL17371826 | 0.79 | TDP1 (0.42) | CYP19A1ALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL27357707 | 0.79 | L3MBTL1 (0.42) | CYP19A1ALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL11569510 | 0.79 | ALOX15 (0.47) | CYP19A1ALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL4065601 | 0.79 | TDP1 (0.42) | CYP19A1TDP1ATML3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896574-A2 | D-AMINO ACID DEHYDROGENASE AND METHOD OF MAKING D-AMINO ACIDS | BioCatalytics Inc. (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006113085-A2 | D-AMINO ACID DEHYDROGENASE AND METHOD OF MAKING D-AMINO ACIDS | BIOCATALYTICS, INC. (US) | 2006-10-26 | — | — | WO | disclosed |