Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046577 | 0.84 | KIF11 (0.40) | METKMT2A | |
| SCHEMBL13580043 | 0.82 | MET (0.58) | METORAI1ALDH1A1LMNA | |
| SCHEMBL5046797 | 0.81 | MAOB (0.40) | METORAI1OPRK1OPRD1OPRM1 | |
| SCHEMBL5046612 | 0.80 | GRM5 (0.37) | METORAI1OPRK1OPRD1KMT2A | |
| SCHEMBL983930 | 0.80 | MET (0.58) | METORAI1OPRD1ALDH1A1LMNA | |
| SCHEMBL1427173 | 0.80 | MET (0.58) | METORAI1MEN1KMT2AALDH1A1 | |
| SCHEMBL981593 | 0.77 | MET (0.55) | METORAI1OPRK1MEN1KMT2A | |
| SCHEMBL5046607 | 0.77 | MET (0.68) | METORAI1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5050480 | 0.76 | MET (0.67) | METORAI1MEN1KMT2AALDH1A1 | |
| SCHEMBL1427200 | 0.75 | MET (0.53) | METORAI1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249095-A1 | 1-Acyldihydropyrazole Derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2008-10-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249095-A1 | 1-Acyldihydropyrazole Derivatives | MET, FLT3, ERBB3 | MET 1/4885ORAI1 4824/4885OPRK1 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.